Tumors: scRNA-seq has proven to be an invaluable tool in understanding the mechanisms behind tumor development. Its application in tumor analysis has shed light on previously overlooked or underappreciated cell populations. For instance, scRNA-seq studies of pancreatic ductal adenocarcinoma (PDA) highlighted the importance and heterogeneity of cancer-associated fibroblasts (CAFs). It was discove..

출처 : Nat Rev Bioengineering (2023) ■ Lipid Nanoparticles in the Development of Nucleic Acid Therapeutics Lipid nanoparticles (LNPs) are an FDA-approved delivery technology used for delivering siRNA to the liver and mRNA vaccines. During the COVID-19 pandemic, LNP-based mRNA vaccines played a crucial role in preventing and blocking infections, drawing significant attention to lipid nanoparticle d..

Applications of Nanobioengineering: 1. Nanobiosensors and Biochips: To understand biological phenomena and apply them in engineering, it is essential to measure biomolecules that exist in trace amounts. Biological detection technology is crucial not only for initially obtaining large amounts of bioinformation but also for industrial applications like disease prevention and diagnosis. For systems..