Dose-Response Relationship

2024. 10. 26. 15:50Drug receptor



The dose or concentration-response curve (DRC or CRC) of a drug indicates the response with variable dose. Pharmacodynamic principles measuring efficacy and potency can be quantified using dose-response curves. In general, gradual dose-response relationships of the drug reflects the number of receptors that are effectively occupied. DRC generally showed between response and log dose of a drug over the response vs dose because (i) a wide range of drug doses can be easily displayed on a single graph and (ii) Comparison between agonists and study of antagonists becomes easier.

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